Mdivi-1
Mdivi-1 (Mitochondrial division inhibitor 1) is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM. Mdivi-1 attenuates mitophagy and enhances apoptosis.
| Trivial name | Mitochondrial division inhibitor 1 |
| Catalog Number | S7162 |
| Molecular Formula | C15H10Cl2N2O2S |
| CAS# | 338967-87-6 |
| Inchi | InChI=1S/C15H10Cl2N2O2S/c1-21-13-7-12(9(16)6-10(13)17)19-14(20)8-4-2-3-5-11(8)18-15(19)22/h2-7H,1H3,(H,18,22) |
| Inchi Key | NZJKEVWTYMOYOR-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C(=C1)N2C(=O)C3=CC=CC=C3NC2=S)Cl)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/mdivi-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Mdivi-1-chemical-structure-s7162.gif |