Ispinesib (SB-715992)
Ispinesib (SB-715992, CK0238273) is a potent, specific and reversible inhibitor of kinesin spindle protein (KSP) with Ki app of 1.7 nM in a cell-free assay, no inhibition to CENP-E, RabK6, MCAK, MKLP1, KHC or Kif1A. Ispinesib induces mitotic arrest and apoptotic cell death.
| Trivial name | CK0238273 |
| Catalog Number | S1452 |
| Molecular Formula | C26H29ClN2O4S |
| CAS# | 336113-53-2 |
| Inchi | InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+ |
| Inchi Key | LLLQTDSSHZREGW-AATRIKPKSA-N |
| SMILES | CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/Ispinesib-mesilate(SB-715992).html |
| Additional Information | https://file.selleck.cn/downloads/struct/Ispinesib-SB-715992-chemical-structure-S1452.gif |