Etoposide
Etoposide is a semisynthetic derivative of podophyllotoxin, which inhibits DNA synthesis via topoisomerase II inhibition activity which enhances double-strand and single-strand cleavage of DNA and reversibly inhibits repair by topoisomerase II binding. Etoposide induces autophagy, mitophagy and apoptosis.
| Trivial name | VP-16213,VP-16 |
| Catalog Number | S1225 |
| Molecular Formula | C26H32ClFO5 |
| CAS# | 33419-42-0 |
| Inchi | InChI=1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1 |
| Inchi Key | FBRAWBYQGRLCEK-AVVSTMBFSA-N |
| SMILES | CCCC(=O)OC1(C(CC2C1(CC(=O)C3(C2CCC4=CC(=O)C=CC43C)F)C)C)C(=O)CCl |
| Size | 500mg |
| Supplier Page | http://www.selleckchem.com/products/Etopophos.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Etoposide-Etopophos-chemical-structure-S1225.gif |