VU0071063
VU0071063 activates heterologously expressed Kir6.2/SUR1 channels with a EC50 of 7 μM, dose dependently and reversibly hyperpolarizes the β-cell membrane potential, which, in turn, inhibits glucose-stimulated Ca2+ entry and insulin secretion.
Trivial name | N/A |
Catalog Number | S6978 |
Molecular Formula | C18H22N4O2 |
CAS# | 333415-38-6 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | CN1C(=O)N(C)C2=C([N](CC3=CC=C(C=C3)C(C)(C)C)C=N2)C1=O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/vu0071063.html |
Additional Information | https://file.selleck.cn/downloads/struct/s6978-vu0071063-chemical-structure.gif |