ZM 447439
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
| Trivial name | N/A |
| Catalog Number | S1103 |
| Molecular Formula | C6H10N2O5 |
| CAS# | 331771-20-1 |
| Inchi | InChI=1S/C6H10N2O5/c7-4(9)1-8(2-5(10)11)3-6(12)13/h1-3H2,(H2,7,9)(H,10,11)(H,12,13) |
| Inchi Key | QZTKDVCDBIDYMD-UHFFFAOYSA-N |
| SMILES | C(C(=O)N)N(CC(=O)O)CC(=O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ZM-447439.html |
| Additional Information | https://file.selleck.cn/downloads/struct/ZM-447439-chemical-structure-S1103.gif |