ZM 447439
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
Trivial name | N/A |
Catalog Number | S1103 |
Molecular Formula | C2H6S3 |
CAS# | 331771-20-1 |
Inchi | InChI=1S/C2H6S3/c1-3-5-4-2/h1-2H3 |
Inchi Key | YWHLKYXPLRWGSE-UHFFFAOYSA-N |
SMILES | CSSSC |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/ZM-447439.html |
Additional Information | https://file.selleck.cn/downloads/struct/ZM-447439-chemical-structure-S1103.gif |