Col003
Col003 is a potent inhibitor of Hsp47 that competitively binds to the collagen-binding site on Hsp47 and inhibited the interaction between Hsp47 and collagen with an IC50 of 1.8 μM. It can be used in research as a potential lead compound for the treatment of fibrosis.
| Catalog Number | E5996 |
| Molecular Formula | C27H44O3 |
| CAS# | 328565-16-8 |
| Inchi | InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23,24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1 |
| Inchi Key | GMRQFYUYWCNGIN-NKMMMXOESA-N |
| SMILES | CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/col003.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5996-Col003-chemical-structure.png |