AG-14361
AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM in a cell-free assay. It is at least 1000-fold more potent than the benzamides.
| Trivial name | N/A |
| Catalog Number | S2178 |
| Molecular Formula | C19H20N4O |
| CAS# | 328543-09-5 |
| Inchi | InChI=1S/C19H20N4O/c1-22(2)12-13-6-8-14(9-7-13)18-21-16-5-3-4-15-17(16)23(18)11-10-20-19(15)24/h3-9H,10-12H2,1-2H3,(H,20,24) |
| Inchi Key | SEKJSSBJKFLZIT-UHFFFAOYSA-N |
| SMILES | CN(C)CC1=CC=C(C=C1)C2=NC3=CC=CC4=C3N2CCNC4=O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/AG14361.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AG14361-chemical-structure-S2178.gif |