Zidovudine-[13C,d3]
Labelled Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor that, following triphosphorylation by thymidine kinase, potently blocks replication of HIV (EC50 = 3 nM) with low cytotoxicity (CC50 > 5 μM). It is commonly used in combination therapy to slow the replication of HIV in vivo.
| Catalog Number | BLP-007638 |
| Alternative Name(s) | 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione-13CD3 |
| Molecular Formula | C9[13C]H10D3N5O4 |
| CAS# | 325484-33-1 |
| Purity | ≥90% |
| Inchi | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1/i1+1D3 |
| Inchi Key | HBOMLICNUCNMMY-JOUPVGMFSA-N |
| Size | Please inquire |
| Supplier Page | https://isotope.bocsci.com/product/zidovudine-13c-d3-cas-325484-33-1-355631.html |