BIBR 1532
BIBR 1532 is a potent, selective, non-competitive telomerase inhibitor with IC50 of 100 nM in a cell-free assay. No inhibition of DNA and RNA polymerases, including HIV reverse transcriptase are observed at concentrations vastly exceeding the IC50 for telomerase. BIBR 1532 induces apoptosis in cancer cells.
| Trivial name | N/A |
| Catalog Number | S1186 |
| Molecular Formula | C21H17NO3 |
| CAS# | 321674-73-1 |
| Inchi | InChI=1S/C21H17NO3/c1-14(16-11-10-15-6-2-3-7-17(15)13-16)12-20(23)22-19-9-5-4-8-18(19)21(24)25/h2-13H,1H3,(H,22,23)(H,24,25)/b14-12+ |
| Inchi Key | PGFQXGLPJUCTOI-WYMLVPIESA-N |
| SMILES | CC(=CC(=O)NC1=CC=CC=C1C(=O)O)C2=CC3=CC=CC=C3C=C2 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/BIBR1532.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BIBR1532-chemical-structure-S1186.gif |