Tacrine
Tacrine is a potent acetylcholinesterase (AChE) inhibitor. It inhibits acetylcholinesterase(AChE) and butyrylcholinesterase(BChE) with an IC50 of 77 nM and 69 nM, respectively. It is used in the treatment of Alzheimer’s disease (AD), also poisoning topoisomerases and inhibiting in vivo (mitochondrial)mtDNA synthesis.
| Catalog Number | E4822 |
| Molecular Formula | C7H5IN2O3 |
| CAS# | 321-64-2 |
| Inchi | InChI=1S/C7H5IN2O3/c8-5-2-1-4(7(9)11)3-6(5)10(12)13/h1-3H,(H2,9,11) |
| Inchi Key | MDOJTZQKHMAPBK-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1C(=O)N)[N+](=O)[O-])I |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/tacrine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4822-Tacrine-chemical-structure.png |