5-Azacytidine
A potent growth inhibitor and cytotoxic agent; a potent DNA methyltransferase inhibitor. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes. Also recently shown to increase reprogramming efficiency of stem cells 10-fold.
| Catalog Number | ABS-002 |
| Alternative Name(s) | 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one, Ladakamycin |
| CAS# | 320-67-2 |
| Inchi | InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16) |
| Inchi Key | NMUSYJAQQFHJEW-UHFFFAOYSA-N |
| SMILES | C1=NC(=NC(=O)N1C2C(C(C(O2)CO)O)O)N |
| Size | Inquiry |
| Supplier Page | https://www.agingclocks.com/5-azacytidine-item-1468.html |