SIB 1757
SIB 1757 is a highly selective, noncompetitive antagonist of metabotropic glutamate receptor type 5 (mGluR5) with IC50 of 0.4 μM at hmGluR5 compared with >30 µM at hmGluR1b, hmGluR2, hmGluR4, hmGluR6, hmGluR7 and hmGluR8.
| Trivial name | N/A |
| Catalog Number | S2645 |
| Molecular Formula | C24H29N5O3.C24H29NO5.5/2H2O.3Na |
| CAS# | 31993-01-8 |
| SMILES | [Na+].[Na+].[Na+].CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=N[NH]3)C(C(C)C)C(O)=O.CCOC(=O)C(C)CC(CC4=CC=C(C=C4)C5=CC=CC=C5)NC(=O)CCC(O)=O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sib-1757.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sib-1757-chemical-structure-s2645.gif |
