SIB 1757
SIB 1757 is a highly selective, noncompetitive antagonist of metabotropic glutamate receptor type 5 (mGluR5) with IC50 of 0.4 μM at hmGluR5 compared with >30 µM at hmGluR1b, hmGluR2, hmGluR4, hmGluR6, hmGluR7 and hmGluR8.
| Trivial name | N/A |
| Catalog Number | S2645 |
| Molecular Formula | C12H11N3O |
| CAS# | 31993-01-8 |
| Inchi | InChI=1S/C12H11N3O/c1-9-7-8-11(16)12(13-9)15-14-10-5-3-2-4-6-10/h2-8,16H,1H3/b15-14+ |
| Inchi Key | LOCPVWIREQIGNQ-CCEZHUSRSA-N |
| SMILES | CC1=NC(=C(C=C1)O)N=NC2=CC=CC=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/sib-1757.html |
| Additional Information | https://file.selleck.cn/downloads/struct/sib-1757-chemical-structure-s2645.gif |