LY-466195 | MedChemExpress (MCE)
LY-466195 is a selective and competitive GLUK5 receptor antagonist. LY-466195 antagonizes Kainate-induced currents with an IC50 value of 0.045 μM in rat dorsal root ganglion neurons. In HEK293 cells transfected with GLUK5, GLUK2/GLUK5, or GLUK5/GLUK66 receptors, LY466195 produces IC50 values of 0.08 μM, 0.34 μM, and 0.07 μM, respectively[1].
| Trivial name | LY-466195 |
| Catalog Number | HY-19858 |
| Research Area | Neurological Disease |
| CAS# | 317844-33-0 |
| Purity | ≥98.00% |
| SMILES | O=C([C@H]1NC[C@]2([H])CC[C@H](CN3[C@H](C(O)=O)CC(F)(F)C3)C[C@]2([H])C1)O |
| PubChem Chemical Structure ID | 9935648 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/ly-466195.html |