JK 184
An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC50 = 210 nM).
Catalog Number | ABS-032 |
Alternative Name(s) | N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-y l)-2-thiazolamine |
CAS# | 315703-52-7 |
Inchi | InChI=1S/C19H18N4OS/c1-3-24-15-9-7-14(8-10-15)21-19-22-16(12-25-19)18-13(2)20-17-6-4-5-11-23(17)18/h4-12H,3H2,1-2H3,(H,21,22) |
Inchi Key | ROYXIPOUVGDTAO-UHFFFAOYSA-N |
SMILES | CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C |
Size | Inquiry |
Supplier Page | https://www.agingclocks.com/jk-184-item-1498.html |