JK 184

An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC50 = 210 nM).

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Catalog Number ABS-032
Alternative Name(s) N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-y l)-2-thiazolamine
CAS# 315703-52-7
Inchi InChI=1S/C19H18N4OS/c1-3-24-15-9-7-14(8-10-15)21-19-22-16(12-25-19)18-13(2)20-17-6-4-5-11-23(17)18/h4-12H,3H2,1-2H3,(H,21,22)
Inchi Key ROYXIPOUVGDTAO-UHFFFAOYSA-N
SMILES CCOC1=CC=C(C=C1)NC2=NC(=CS2)C3=C(N=C4N3C=CC=C4)C
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Supplier Page https://www.agingclocks.com/jk-184-item-1498.html