STF-62247
STF-62247 is a molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. STF-62247 shows selective toxicity and growth inhibition of renal cells lacking VHL; 25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+).
Trivial name | N/A |
Catalog Number | S1041 |
Molecular Formula | C15H13N3S |
CAS# | 315702-99-9 |
Inchi | InChI=1S/C15H13N3S/c1-11-3-2-4-13(9-11)17-15-18-14(10-19-15)12-5-7-16-8-6-12/h2-10H,1H3,(H,17,18) |
Inchi Key | KATNUHQNJGNLPW-UHFFFAOYSA-N |
SMILES | CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3 |
Size | 10mg |
Supplier Page | http://www.selleckchem.com/products/STF-62247.html |
Additional Information | https://file.selleck.cn/downloads/struct/STF-62247-chemical-structure-S1041.gif |