BTSA1
BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
| Trivial name | N/A |
| Catalog Number | S8650 |
| Molecular Formula | C21H14N6OS2 |
| CAS# | 314761-14-3 |
| Inchi | InChI=1S/C21H14N6OS2/c28-19-18(24-25-20-22-11-12-29-20)17(15-9-5-2-6-10-15)26-27(19)21-23-16(13-30-21)14-7-3-1-4-8-14/h1-13H,(H,22,25)/b24-18+ |
| Inchi Key | KYVZVVOQWWCVPP-HKOYGPOVSA-N |
| SMILES | C1=CC=C(C=C1)C2=CSC(=N2)N3C(=O)C(=C(N3)C4=CC=CC=C4)N=NC5=NC=CS5 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/btsa1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/btsa1-chemical-structure-s8650.gif |