IU1
IU1 is a cell-permeable, reversible and selective proteasome inhibitor of human USP14 with IC50 of 4.7 μ M, 25-fold selective to IsoT. IU1 induces autophagy.
| Trivial name | N/A |
| Catalog Number | S7134 |
| Molecular Formula | C18H21FN2O |
| CAS# | 314245-33-5 |
| Inchi | InChI=1S/C18H21FN2O/c1-13-11-17(18(22)12-20-9-3-4-10-20)14(2)21(13)16-7-5-15(19)6-8-16/h5-8,11H,3-4,9-10,12H2,1-2H3 |
| Inchi Key | JUWDSDKJBMFLHE-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)CN3CCCC3 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/iu1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/IU1-chemical-structure-s7134.gif |