Ucf-101
Ucf-101 is a selective and competitive inhibitor of pro-apoptotic protease Omi/HtrA2, with an IC50 of 9.5 μM for His-Omi. Ucf-101 exhibits very little activity against various other serine proteases (IC50>200 μM). Ucf-101 has a natural red fluorescence at 543 nm that is used to monitor its ability to enter mammalian cells. Ucf-101 has a significant cardioprotective effect against MI/R injury and also has certain neuroprotective effect.
| Catalog Number | E8075 |
| Molecular Formula | C19H22N2O |
| CAS# | 313649-08-0 |
| Inchi | InChI=1S/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/t13-,14?,18+,19-/m0/s1 |
| Inchi Key | KMPWYEUPVWOPIM-FGVBSWQGSA-N |
| SMILES | C=CC1CN2CCC1CC2C(C3=CC=NC4=CC=CC=C34)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ucf-101.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8075-ucf-101-chemical-structure-tube.png |