4-Hydroxyestrone
4-Hydroxyestrone (4-OHE1), an estrone metabolite, has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. 4-Hydroxyestrone has little estrogenic activity.
| Trivial name | 4-OHE1 |
| Catalog Number | E8109 |
| Molecular Formula | C28H44O |
| CAS# | 3131-23-5 |
| Inchi | InChI=1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1 |
| Inchi Key | DNVPQKQSNYMLRS-APGDWVJJSA-N |
| SMILES | CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2=CC=C4C3(CCC(C4)O)C)C |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/4-hydroxyestrone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8109-4-hydroxyestrone-chemical-structure-tube.png |