Hycanthone
Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.
| Catalog Number | E7866 |
| Molecular Formula | C31H33N2O3.HCl |
| CAS# | 3105-97-3 |
| Inchi | InChI=1S/C31H33ClN2O3.ClH/c1-20(2)28(34(17-7-16-33)31(36)23-12-10-21(3)11-13-23)30-26(18-22-8-5-4-6-9-22)29(35)25-15-14-24(32)19-27(25)37-30;/h4-6,8-15,19-20,28H,7,16-18,33H2,1-3H3;1H/t28-;/m1./s1 |
| Inchi Key | MLMZVWABFOLFGV-LNLSOMNWSA-N |
| SMILES | CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=C(C(=O)C3=C(O2)C=C(C=C3)Cl)CC4=CC=CC=C4)C(C)C.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/hycanthone.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7866-hycanthone-chemical-structure-tube.png |