MCB-22-174

MCB-22-174 is a potent agonist of Piezo1, with an EC50 value of 6.28 µM. It activates the Ca2+-related extracellular signal-related kinases and calcium–calmodulin (CaM)-dependent protein kinase II (CaMKII) pathway and promotes mesenchymal stem cells osteoblastic differentiation, exhibiting its potential use in research for the treatment of disuse osteoporosis (OP).

Price Not Available 100mg MCB-22-174 Supplier Page

Catalog Number	E4756
Molecular Formula	C31H42N6O4
CAS#	3058199-58-6
Inchi	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)
Inchi Key	UXXQOJXBIDBUAC-UHFFFAOYSA-N
SMILES	CC(C)OC1=CC=C(C=C1)NC(=O)N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCCC5
Size	100mg
Supplier Page	http://www.selleckchem.com/products/mcb-22-174.html
Additional Information	https://file.selleck.cn/downloads/struct/E4756-MCB-22-174-chemical-structure.png