SD-2301
SD-2301 is a potent and selective PROTAC-based STAT3 degrader that targets the VHL–cullin 2 complex, enhancing dendritic cell function and anti-tumor immunity. It synergizes with anti-PD-L1 therapy to robustly suppress tumor growth in vivo.
| Catalog Number | E6446 |
| Molecular Formula | C19H27N3O4 |
| CAS# | 3054116-24-1 |
| Inchi | InChI=1S/C19H27N3O4/c1-11(2)16(23)18(25)20-12(3)17(24)21-15-14-8-6-5-7-13(14)9-10-22(4)19(15)26/h5-8,11-12,15-16,23H,9-10H2,1-4H3,(H,20,25)(H,21,24)/t12-,15-,16-/m0/s1 |
| Inchi Key | PKXWXXPNHIWQHW-RCBQFDQVSA-N |
| SMILES | CC(C)C(C(=O)NC(C)C(=O)NC1C2=CC=CC=C2CCN(C1=O)C)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/sd-2301.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E6446-SD-2301-chemical-structure.png |