Zidovudine
Zidovudine (ZDV, Azidothymidine, NSC 602670) is a nucleoside analogue reverse transcriptase inhibitor, used to treat HIV. It could decrease the HDR efficiency and decrease CRISPR-mediated sequence-specific genome knockin events while increaseing knockout efficiency.
| Trivial name | Azidothymidine, NSC 602670 |
| Catalog Number | S2579 |
| Molecular Formula | C10H13N5O4 |
| CAS# | 30516-87-1 |
| Inchi | InChI=1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1 |
| Inchi Key | HBOMLICNUCNMMY-XLPZGREQSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-] |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/zidovudine-retrovir.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Zidovudine-retrovir-chemical-structure-s2579.gif |