Cpd. 37
MYC-IN-3 (Cpd. 37) is an alkynyl-substituted phenylpyrazole derivative and an inhibitor of MYC function by disrupting MYC/MAX interaction with an IC50 of 1.27 μM in PC3 cells and preventing MYC/MAX binding to DNA. It exhibits antiproliferative activity against multiple malignant cell lines and demonstrates enhanced therapeutic efficacy in a mouse allograft model of prostate cancer.
| Trivial name | MYC-IN-3 |
| Catalog Number | E4750 |
| Molecular Formula | C25H52NO4P |
| CAS# | 3042878-82-7 |
| Inchi | InChI=1S/C25H52NO4P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29-31(27,28)30-25-20-22-26(2,3)23-21-25/h25H,4-24H2,1-3H3 |
| Inchi Key | SZFPYBIJACMNJV-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCOP(=O)([O-])OC1CC[N+](CC1)(C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/cpd-37.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4750-Cpd-37-chemical-structure.png |