VVD-130037(BAY-3605349)

VVD-130037(BAY-3605349) is an orally available covalent small molecule activator of Kelch-like ECH associated protein 1 (KEAP1), which provide enhanced cellular degradation of nuclear factor-erythroid 2 p45-related factor 2 (NRF2) resulting in significant inhibition of tumor growth in advanced solid tumors.

Price Not Available 5mg VVD-130037(BAY-3605349) Supplier Page
Trivial name BAY-3605349
Catalog Number E4728
Molecular Formula C29H26ClFN4O4S.2C7H8O3S
CAS# 3034880-93-5
Inchi InChI=1S/C29H26ClFN4O4S.2C7H8O3S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19;2*1-6-2-4-7(5-3-6)11(8,9)10/h2-10,13-15, 18,32H,11-12,16-17H2,1H3,(H,33,34,35);2*2-5H,1H3,(H,8,9,10)
Inchi Key UWYXLGUQQFPJRI-UHFFFAOYSA-N
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
Size 5mg
Supplier Page http://www.selleckchem.com/products/vvd-130037.html
Additional Information https://file.selleck.cn/downloads/struct/E4728-VVD-130037-BAY-3605349-chemical-structure.png