VVD-130037(BAY-3605349)

VVD-130037(BAY-3605349) is an orally available covalent small molecule activator of Kelch-like ECH associated protein 1 (KEAP1), which provide enhanced cellular degradation of nuclear factor-erythroid 2 p45-related factor 2 (NRF2) resulting in significant inhibition of tumor growth in advanced solid tumors.

Price Not Available 1g VVD-130037(BAY-3605349) Supplier Page
Trivial name BAY-3605349
Catalog Number E4728
Molecular Formula C13H13N3O3
CAS# 3034880-93-5
Inchi InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)
Inchi Key GOTYRUGSSMKFNF-UHFFFAOYSA-N
SMILES C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N
Size 1g
Supplier Page http://www.selleckchem.com/products/vvd-130037.html
Additional Information https://file.selleck.cn/downloads/struct/E4728-VVD-130037-BAY-3605349-chemical-structure.png