Dasatinib
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
| Trivial name | BMS-354825 |
| Catalog Number | S1021 |
| Molecular Formula | C16H12N4O9S2.3Na |
| CAS# | 302962-49-8 |
| Inchi | InChI=1S/C16H12N4O9S2.3Na/c21-15-13(18-17-9-1-5-11(6-2-9)30(24,25)26)14(16(22)23)19-20(15)10-3-7-12(8-4-10)31(27,28)29;;;/h1-8,13H,(H,22,23)(H,24,25,26)(H,27,28,29);;;/q;3*+1/p-3/b18-17+;;; |
| Inchi Key | UJMBCXLDXJUMFB-GLCFPVLVSA-K |
| SMILES | C1=CC(=CC=C1N=NC2C(=NN(C2=O)C3=CC=C(C=C3)S(=O)(=O)[O-])C(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+].[Na+] |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/Dasatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Dasatinib-BMS-354825-chemical-structure-S1021.gif |