Dasatinib
Dasatinib is a novel, potent and multi-targeted inhibitor that targets Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM in cell-free assays, respectively. Dasatinib induces autophagy and apoptosis with anti-tumor activity.
| Trivial name | BMS-354825 |
| Catalog Number | S1021 |
| Molecular Formula | C22H26ClN7O2S |
| CAS# | 302962-49-8 |
| Inchi | InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27) |
| Inchi Key | ZBNZXTGUTAYRHI-UHFFFAOYSA-N |
| SMILES | CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/Dasatinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Dasatinib-BMS-354825-chemical-structure-S1021.gif |