RS47
RS47 is a potent and specific inhibitor of the non-canonical NF-κB signaling pathway through disrupting RelB binding to its target DNA with a Kd values of 1.1 μM. It is shown to inhibit colorectal cancer (CRC) cells and B lymphoma growth, holds potential as a research tool for targeting cancers driven by hyperactive non-canonical NF-κB signaling.
| Catalog Number | E5916 |
| Molecular Formula | C25H37NO4 |
| CAS# | 301655-16-3 |
| Inchi | InChI=1S/C25H37NO4/c1-2-26-25(30)13-9-4-3-8-12-21-22(24(29)18-23(21)28)17-16-20(27)15-14-19-10-6-5-7-11-19/h3,5-8,10-11,16-17,20-24,27-29H,2,4,9,12-15,18H2,1H3,(H,26,30)/b8-3-,17-16+/t20?,21-,22-,23+, 24+/m1/s1 |
| Inchi Key | AQOKCDNYWBIDND-GLQITXMVSA-N |
| SMILES | CCNC(=O)CCCC=CCC1C(CC(C1C=CC(CCC2=CC=CC=C2)O)O)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/rs47.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5916-RS47-chemical-structure.png |