JGB-1-155 | MedChemExpress (MCE)
JGB-1-155 is a positive allosteric modulators (N-PAMs), which enhances the activity of nicotinamide phosphoribosyltransferase NAMPT with EC50 of 3.29 μM. JGB-1-155 counteracts the oxidative stress, through upregulating the NAD+ in THP-1 human monocytes. JGB-1-155 attenuates TNFα-induced ROS in HT-22 cells [1].
| Trivial name | JGB-1-155 |
| Catalog Number | HY-163280 |
| Research Area | Neurological Disease |
| CAS# | 3011930-28-9 |
| Purity | ≥98.0% |
| SMILES | O=C(N(CCC1(C(C)C)CCOC(C)(C1)C)CC2=CC=C(N(C)C)C=C2)C3=CC=CO3 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/jgb-1-155.html |