JGB-1-155 | MedChemExpress (MCE)

JGB-1-155 is a positive allosteric modulators (N-PAMs), which enhances the activity of nicotinamide phosphoribosyltransferase NAMPT with EC50 of 3.29 μM. JGB-1-155 counteracts the oxidative stress, through upregulating the NAD+ in THP-1 human monocytes. JGB-1-155 attenuates TNFα-induced ROS in HT-22 cells [1].

Trivial name JGB-1-155
Catalog Number HY-163280
Research Area Neurological Disease
CAS# 3011930-28-9
Purity ≥98.0%
SMILES O=C(N(CCC1(C(C)C)CCOC(C)(C1)C)CC2=CC=C(N(C)C)C=C2)C3=CC=CO3
Size 1 mg
Supplier Page https://www.medchemexpress.com/jgb-1-155.html