ATF4-IN-1 | MedChemExpress (MCE)
ATF4-IN-1 (Compound 21) is an ATF4 inhibitor. ATF4-IN-1 inhibits ATF4 expression in Thapsigargin (HY-13433)-stimulated
HEK-293T cells, with an IC50 value of 32.43 nM. ATF4-IN-1 is more active than ISRIB (HY-12495A). ATF4-IN-1 exhibits low cytotoxicity (IC50: 96 μM against HEK-293T cells). ATF4-IN-1 can be used for research of neurodegenerative diseases[1].
| Trivial name | ATF4-IN-1 |
| Catalog Number | HY-158201 |
| Research Area | Neurological Disease |
| CAS# | 2991057-76-0 |
| Purity | ≥98.0% |
| SMILES | O=C(N[C@H]1CC[C@H](C2=NN=C(C3=CC4=CC(Cl)=CC=C4O3)O2)CC1)COC5=CC=C(Cl)C=C5 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/atf4-in-1.html |