HDAC6-IN-37 | MedChemExpress (MCE)
HDAC6-IN-37 (compound W5) is an inhibitor of HDAC6 and has neuroprotective effects. HDAC6-IN-37 can restore the morphology of hippocampal neurons, reduce the expression of Aβ, Tau, and p-Tau proteins in the hippocampus of AD rats, and inhibit the formation of senile plaques and neurofibrillary tangles. Thus, HDAC6-IN-37 improves the Aβ/Cu2+-induced AD model in rats, regulates oxidative stress status, and balances neurotransmitter disorders in brain tissue[1].
| Trivial name | HDAC6-IN-37 |
| Catalog Number | HY-158030 |
| Research Area | Neurological Disease |
| CAS# | 2986486-82-0 |
| Purity | ≥98.0% |
| SMILES | O=C(C1=CN=C(C=C1)CN2C3=CC=CC=C3SC4=C2C=CC=C4)NO.Cl |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/hdac6-in-37.html |