ATX968
ATX968 (DHX9-IN-2) is a potent, selective, and orally bioavailable inhibitor of DHX9 helicase with an IC50 of 8 nM. It induces strong and sustained tumor growth inhibition or regression in MSI-H/dMMR colorectal cancer (CRC) xenograft models.
| Trivial name | DHX9-IN-2 |
| Catalog Number | E5836 |
| Molecular Formula | C11H14N2O4 |
| CAS# | 2973395-71-8 |
| Inchi | InChI=1S/C11H14N2O4/c12-10(14)16-6-9(7-17-11(13)15)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,14)(H2,13,15) |
| Inchi Key | WKGXYQFOCVYPAC-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)C(COC(=O)N)COC(=O)N |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/atx968.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5836-ATX968-chemical-structure.png |