AZD0022
AZD0022 is a potent, orally bioavailable, selective, reversible inhibitor of KRASG12D that drives robust pathway inhibition and anti-tumour activity in KRASG12D models.
| Catalog Number | E6405 |
| Molecular Formula | C24H20N6O3 |
| CAS# | 2958627-18-2 |
| Inchi | InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29) |
| Inchi Key | HTQMVQVXFRQIKW-UHFFFAOYSA-N |
| SMILES | CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/azd0022.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E6405-AZD0022-chemical-structure.png |