YDR1
YDR1 is a potent, selective and orally bioavailable Cereblon-based PROTAC and a degrader of SMARCA2 with DC50 of 60 nM at 48 hours. It exhibits antitumor activity in SMARCA4-mutant lung cancer xenograft models and can be used in research on non-small cell lung cancer.
| Trivial name | Flezurafenibum |
| Catalog Number | E8294 |
| Molecular Formula | C17H34O2 |
| CAS# | 2951015-31-7 |
| Inchi | InChI=1S/C17H34O2/c1-4-5-6-7-8-9-10-11-12-13-14-15-17(18)19-16(2)3/h16H,4-15H2,1-3H3 |
| Inchi Key | AXISYYRBXTVTFY-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCC(=O)OC(C)C |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/ydr1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e8294-ydr1-chemical-structure-tube.png |