(R)-G12Di-7 | MedChemExpress (MCE)

(R)-G12Di-7 is a covalent ligand for KRAS-G12D, which selectively labels K-Ras-G12D·GDP and K-Ras-G12D·GppNHp. (R)-G12Di-7 exhibits inhibitory activity against G12D mutated cancer cells[1].

Trivial name (R)-G12Di-7
Catalog Number HY-158008
Research Area Cancer
CAS# 2946593-60-6
Purity ≥98.0%
SMILES C#CC1=C(C=CC2=CC(O)=CC(C3=C(C4=C(C(N5CC6CCC(N6C([C@@H]7OC(C7(C)C)=O)=O)C5)=NC(OC[C@@]89CCCN8C[C@@H](C9)F)=N4)C=N3)F)=C21)F
Size 1 mg
Supplier Page https://www.medchemexpress.com/r-g12di-7.html