PARP1/c-Met-IN-1 | MedChemExpress (MCE)
PARP1/c-Met-IN-1 (Compound 16) is a selective dual inhibitor for PARP1 and c-Met, with IC50s of 3.3 and 32.2 nM, respectively. PARP1/c-Met-IN-1 induces cell apoptosis and cell cycle arrest in G2/M phase in MDA-MB-231 cells. PARP1/c-Met-IN-1 exhibits antitumor activity in mice[1].
| Trivial name | PARP1/c-Met-IN-1 |
| Catalog Number | HY-161372 |
| Research Area | Cancer |
| CAS# | 2944101-99-7 |
| Purity | ≥98.0% |
| SMILES | O=C1C=CC(C2=CC=CN=C2)=NN1CCOC3=C4C(C=C(C=C4)N5CCN(CC5)C(C6=C(C=CC(CC7=NNC(C8=C7C=CC=C8)=O)=C6)F)=O)=NC=C3 |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/parp1-c-met-in-1.html |