T0901317
T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of 20nM for LXRα and 5 μM for FXR, respectively. T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM, respectively. T0901317 significantly suppresses cell proliferation and induces apoptosis.
| Trivial name | N/A |
| Catalog Number | S7076 |
| Molecular Formula | C17H12F9NO3S |
| CAS# | 293754-55-9 |
| Inchi | InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2 |
| Inchi Key | SGIWFELWJPNFDH-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/t0901317.html |
| Additional Information | https://file.selleck.cn/downloads/struct/T0901317-chemical-structure-s7076.gif |