MAO A/HSP90-IN-2 | MedChemExpress (MCE)
MAO A/HSP90-IN-2 (compound 4-C) is a dual inhibitor of HSP90and MAO A with the IC50 values of 0.016 and 4.58 μM, respectively. MAO A/HSP90-IN-2 increases HSP70 expression and reduces HER2 and phospho-Akt expression, and decreases IFN-γ induced PD-L1 expression in GL26 cells. MAO A/HSP90-IN-2 inhibits the growth of Temozolomide (HY-17364) -sensitive and -resistant GBM cells, colon cancer, leukemia, non-small cell lung and other cancers, and has potential to inhibit tumor immune escape[1] sup >.
Trivial name | MAO A/HSP90-IN-2 |
Catalog Number | HY-155580 |
Research Area | Cancer |
CAS# | 2927489-99-2 |
Purity | ≥98.00% |
SMILES | O=C(C1=C(C=C(C(C(C)C)=C1)O)O)N(C2=CC(Cl)=C(C=C2)OCCCN(CC#C)C)CC |
PubChem Chemical Structure ID | 168476167 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/mao-a-hsp90-in-2.html |