MAO A/HSP90-IN-1 | MedChemExpress (MCE)
MAO A/HSP90-IN-1 (4-b) is a MAO A/HSP90 dual inhibitor with IC50 value of 1.77 μM and 0.019 μM in Glioblastoma (GBM) GL26 cells and HSP90α, respectively. MAO A/HSP90-IN-1 (4-b) can inhibit MAO A activity, HSP90 binding and the expression of HER2 and phospho-Akt to inhibit the growth of GBM, they also reduce PD-L1 expression, which inhibits T cell activation. MAO A/HSP90-IN-1 (4-b) have potential to inhibit tumor immune escape. MAO A/HSP90-IN-1 (4-b) can be used for brain tumor-related diseases research[1].
Trivial name | MAO A/HSP90-IN-1 |
Catalog Number | HY-155577 |
Research Area | Cancer |
CAS# | 2927489-95-8 |
Purity | ≥98.00% |
SMILES | CN(C1=CC(Cl)=C(C=C1)OCCCN(CC#C)C)C(C2=C(C=C(C(C(C)C)=C2)O)O)=O |
PubChem Chemical Structure ID | 168510577 |
Size | 1 mg |
Supplier Page | https://www.medchemexpress.com/mao-a-hsp90-in-1.html |