PI3Kα-IN-22 | MedChemExpress (MCE)
PI3Kα-IN-22 (Compound 17) is an orally active, potent and selective inhibitor of PI3KαH1047R, with an IC50 of 1 nM for pAKT T47D AlphaLISA. PI3Kα-IN-22 can induce tumor regressions in the HCC1954 tumor model in mice[1].
| Trivial name | PI3Kα-IN-22 |
| Catalog Number | HY-161373 |
| Research Area | Cancer |
| CAS# | 2925030-26-6 |
| Purity | ≥98.0% |
| SMILES | CC(C=C([C@H](NC1=CC=CC=C1C(O)=O)C)C2=NC(N3CCC(F)(F)CC3)=C4C#N)=CN2C4=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/pi3kα-in-22.html |