PT-179
PT-179, an orthogonal Thalidomide derivative targets cereblon without causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.
Catalog Number | E1937 |
CAS# | 2924858-25-1 |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/pt-179.html |
Additional Information | https://file.selleck.cn/downloads/struct/E1937-PT-179-chemical-structure.png |