EGFR kinase inhibitor 3 | MedChemExpress (MCE)
EGFR kinase inhibitor 3 (compound 2) is a bivalent ATP-allosteric EGFR kinase inhibitor with IC50s of <10 nM, 1.5 nM, 0.059 nM, 0.064 nM for WT EGFR, EGFR-activating mutations L858R, L858R/T790M and L858R/T790M/C797S, respectively. EGFR kinase inhibitor 3 is a C-linked inhibitor[1].
| Trivial name | EGFR kinase inhibitor 3 |
| Catalog Number | HY-162299 |
| Research Area | Cancer |
| CAS# | 2922402-03-5 |
| Purity | ≥98.0% |
| SMILES | O=C(NC1=CC=CC(C2=C(NC(SC)=N2)C3=CC=NC(NC(C)=O)=C3)=C1)C4=C5NC(C6=C(NC5=CC=C4)C=CC=C6)=O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/egfr-kinase-inhibitor-3.html |