LBA-3 | MedChemExpress (MCE)

LBA-3 is a selective, orally active inhibitor for sodium-coupled citrate transporter SLC13A5, with an IC50 of 67 nM. LBA-3 decreases levels of triglyceride and total cholesterol in oleic and palmitic acid (OPA)-stimulated AML12 cells, PCN-stimulated primary mouse hepatocytes and in mouse models, without detectable toxicity. LBA-3 is blood-brain barrier permeable[1].

Trivial name LBA-3
Catalog Number HY-158160
Research Area Metabolic Disease
CAS# 2918263-09-7
Purity ≥98.0%
SMILES O=C(C(CCC1=CC=C(C=C1)C2=CC=CC=C2)(CC(O)=O)O)O
Size 1 mg
Supplier Page https://www.medchemexpress.com/lba-3.html