LBA-3 | MedChemExpress (MCE)
LBA-3 is a selective, orally active inhibitor for sodium-coupled citrate transporter SLC13A5, with an IC50 of 67 nM. LBA-3 decreases levels of triglyceride and total cholesterol in oleic and palmitic acid (OPA)-stimulated AML12 cells, PCN-stimulated primary mouse hepatocytes and in mouse models, without detectable toxicity. LBA-3 is blood-brain barrier permeable[1].
| Trivial name | LBA-3 |
| Catalog Number | HY-158160 |
| Research Area | Metabolic Disease |
| CAS# | 2918263-09-7 |
| Purity | ≥98.0% |
| SMILES | O=C(C(CCC1=CC=C(C=C1)C2=CC=CC=C2)(CC(O)=O)O)O |
| Size | 1 mg |
| Supplier Page | https://www.medchemexpress.com/lba-3.html |