VLS-1488(KIF18A-IN-6 )
VLS-1488 (KIF18A-IN-6) is an oral inhibitor of KIF18A with an IC50 of 0.016 μM. KIF18A is a mitotic kinesin motor protein that localizes at the plus-end of kinetochore microtubule spindle fibers and is crucial for cell division in aneuploid cancer cells with high chromosomal instability (CIN).
| Trivial name | KIF18A-IN-6 |
| Catalog Number | E4602 |
| Molecular Formula | C16H14N2O2 |
| CAS# | 2914879-10-8 |
| SMILES | CC1=CC2=NC=C(N=C2C=C1C)C3=CC(=C(C=C3)O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/vls-1488-kif18a-in-6.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4602-VLS-1488-KIF18A-IN-6-chemical-structure.png |