VLS-1488(KIF18A-IN-6 )
VLS-1488 (KIF18A-IN-6) is an oral inhibitor of KIF18A with an IC50 of 0.016 μM. KIF18A is a mitotic kinesin motor protein that localizes at the plus-end of kinetochore microtubule spindle fibers and is crucial for cell division in aneuploid cancer cells with high chromosomal instability (CIN).
Trivial name | KIF18A-IN-6 |
Catalog Number | E4602 |
Molecular Formula | C13H9BrO3 |
CAS# | 2914879-10-8 |
SMILES | C1=CC=C(C=C1)C2=CC(=C(C(=C2)Br)O)C(=O)O |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/vls-1488-kif18a-in-6.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4602-VLS-1488-KIF18A-IN-6-chemical-structure.png |