Senicapoc (ICA-17043)

Senicapoc (ICA-17043) is a Gardos channel(Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM and produces dose-dependent increases in hemoglobin and decreases in markers of hemolysis. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.

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Catalog Number	E0501
Molecular Formula	C20H15F2NO
CAS#	289656-45-7
SMILES	NC(=O)C(C1=CC=CC=C1)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3
Size	5mg
Supplier Page	http://www.selleckchem.com/products/senicapoc-ica-17043.html
Additional Information	https://file.selleck.cn/downloads/struct/e0501-senicapoc-ica-17043-chemical-structure.gif