CFT-1946

A degrader of B-RAFV600E, B-RAFG469A, and B-RAFG466V

Price Not Available 500 µg CFT-1946 Supplier Page

Catalog Number	44277
Alternative Name(s)	Tagarafdeg
Research Area	Product Type\|Biochemicals\|\|Research Area\|Cancer\|Cell Signaling\|ERK/MAPK Signaling\|\|Research Area\|Cell Biology\|Cell Signaling\|ERK/MAPK Signaling\|\|Research Area\|Cell Biology\|Proteolysis\|Ubiquitin/Proteasome System
Molecular Formula	C45H49F2N11O9S
CAS#	2882165-79-7
Purity	≥98%
Inchi	InChI=1S/C45H49F2N11O9S/c1-4-53(2)68(64,65)52-35-8-6-32(46)40(31(35)24-48)67-28-5-7-34-29(19-28)42(61)58(26-49-34)27-22-45(66-25-27)12-17-56(18-13-45)39(60)23-44(63)10-15-55(16-11-44)37-21-36-30(20-33(37)47)41(51-54(36)3)57-14-9-38(59)50-43(57)62/h5-8,19-21,26-27,52,63H,4,9-18,22-23,25H2,1-3H3,(H,50,59,62)/t27-/m1/s1
Inchi Key	OCDRMYDQTIPVOI-HHHXNRCGSA-N
SMILES	CN1C2=CC(N3CCC(CC(N4CCC5(C[C@@H](N6C(C7=CC(OC8=C(C(NS(N(C)CC)(=O)=O)=CC=C8F)C#N)=CC=C7N=C6)=O)CO5)CC4)=O)(CC3)O)=C(F)C=C2C(N9CCC(NC9=O)=O)=N1
Size	500 µg
Supplier Page	https://www.caymanchem.com/product/44277