Euphorbiasteroid
Euphorbiasteroid (Euphorbia factor L1), a component of Euphorbia lathyris L., inhibits adipogenesis of 3T3-L1 cells through activation of the AMPK pathway and induces HL-60 cells to apoptosis via promoting Bcl-2/Bax apoptotic signaling pathway in a dose-dependent manner. Euphorbiasteroid is a tricyclic diperpene of Euphorbia lathyris L., inhibits tyrosinase, and increases the phosphorylation of AMPK, with anti-cancer, anti-virus, anti-obesity and multidrug resistance-modulating effect.
Trivial name | Euphorbia factor L1 |
Catalog Number | S3832 |
Molecular Formula | C32H40O8 |
CAS# | 28649-59-4 |
Inchi | InChI=1S/C32H40O8/c1-18-14-24-23(30(24,5)6)12-13-31(17-37-31)29(38-20(3)33)26-27(39-25(35)15-22-10-8-7-9-11-22)19(2)16-32(26,28(18)36)40-21(4)34/h7-11,14,19,23-24,26-27,29H,12-13,15-17H2,1-6H3/b18-14/t19-,23-,24+,26+,27-,29-,31+,32+/m0/s1 |
Inchi Key | SDGDWRYYHQOQOJ-XXMLZKCSSA-N |
SMILES | CC1CC2(C(C1OC(=O)CC3=CC=CC=C3)C(C4(CCC5C(C5(C)C)C=C(C2=O)C)CO4)OC(=O)C)OC(=O)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/euphorbiasteroid.html |
Additional Information | https://file.selleck.cn/downloads/struct/euphorbiasteroid-chemical-structure-S3832.gif |